🧪 Active Ingredient Profile

Permethrin Clothing Treatment for Ticks and Mosquitoes

Synthetic Pyrethroid (Clothing Application)

Permethrin-treated clothing is the CDC and military recommended approach for tick and mosquito protection in the field. Unlike skin repellents that wear off in hours, permethrin bonds to fabric fibers and remains effective through 6 washes (spray) or 70 washes (factory-treated). It kills ticks on contact within 30 seconds.

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Classification
Synthetic Pyrethroid (Clothing Application)
Signal Word
Caution
Mode of Action
Sodium channel disruptor: contact kill on arthropods that touch treated fabric; bonds to fabric fibers

Target Pests

Ticks (kills on contact in 30-60 seconds - the gold standard for Lyme prevention), mosquitoes (kills and repels), chiggers, mites, biting flies, fleas. The US military has treated uniforms with permethrin since the 1990s for protection against disease-vectoring arthropods in the field.

Products and Brand Names

Sawyer Permethrin Spray (0.5% - the most popular DIY product), Repel Permanone, Ben permethrin spray, Insect Shield (factory-treated clothing - lasts 70 washes), ExOfficio BugsAway clothing line, LL Bean No Fly Zone clothing, REI Co-op permethrin-treated gear. US military ACUs are factory-treated.

๐Ÿ“‹ Safety Data Sheet (SDS)

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Permethrin Clothing Treatment for Ticks and Mosquitoes โ€” Safety Data Sheet

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๐Ÿ“„ Permethrin Clothing Treatment for Ticks and Mosquitoes โ€” Safety Data Sheet ยท View the complete SDS document above or download below

Safety and Precautions

Permethrin is safe on clothing but should NOT be applied to skin (unlike DEET). Once dried on fabric (2-4 hours), it is not absorbed through skin in any meaningful amount. The EPA has concluded that wearing permethrin-treated clothing poses negligible risk to human health.

The CDC-recommended combo: DEET or picaridin on exposed skin + permethrin on clothing = the maximum protection strategy for tick-borne disease prevention. This combination is recommended by the CDC, US Army, and every major tick research institution.
Cats: Wet permethrin is toxic to cats. Treat clothing outdoors and allow to dry completely (2-4 hours minimum) before bringing inside. Once dry and bonded to fabric, treated clothing is safe around cats. Do NOT spray permethrin near cats or allow cats to contact wet-treated items.

Pro Tips

How to treat clothing: Lay garments flat outdoors on a surface you do not mind getting sprayed. Spray Sawyer Permethrin evenly on both sides until lightly damp (not soaking). Treat: pants, socks, shoes, shirt, hat, and backpack. Let dry completely (2-4 hours). Wear normally. Effective through 6 washes or 42 days of sun exposure.

What to treat: Focus on the items ticks contact first: socks, shoes/boots, pant legs, and gaiters. These are the front line of defense. Also treat shirts, hats, and backpacks for mosquito protection.

Factory-treated vs DIY spray: Factory-treated clothing (Insect Shield, ExOfficio BugsAway) lasts 70+ washes and is more evenly distributed. DIY spray (Sawyer) lasts 6 washes but costs less and lets you treat any garment. Both are highly effective.

The 30-second tick kill: In lab studies, ticks placed on permethrin-treated fabric become disoriented within seconds and die within 30-60 seconds. They literally cannot survive contact with properly treated clothing. This is why the military has mandated permethrin treatment for decades.

Did you know? The US military treats over 2 million uniforms with permethrin annually. During field testing in the 1990s, soldiers wearing treated uniforms reported 99.9% fewer tick bites compared to untreated uniforms. This led to the Department of Defense mandating permethrin treatment for all combat uniforms.
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Reviewed by Derek GiordanoContent reviewed by a licensed pest management professional. Last reviewed: April 2026.
๐Ÿ“š Sources: EPA Pesticide Labels ยท NPIC Pesticide Info
Published: Jan 1, 2025 ยท Updated: Apr 7, 2026